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Article

Cell-type specific posttranslational processing of peptides by different pituitary cell lines.

Endocrinology - 1 Jul 1990

Dickerson I M, Mains R E

Abstract excerpt

In order to compare prohormone processing in two distinct pituitary cell types, somatomammotrope cells (GH3) and corticotrope cells (AtT-20) were stably transfected with vectors encoding preproneuropeptide Y (preproNPY) containing four different pairs of basic amino acids at the single endoproteolytic cleavage site: wildtype or KR (lysine-arginine), RR, RK, and KK. The GH-NPY cell lines cleaved proNPY to a...

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Source

Identifiers

PMID: 2193796
DOI: 10.1210/endo-127-1-133

Genes

NPY
PRL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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