Article
Array-based karyotyping for prognostic assessment in chronic lymphocytic leukemia: performance comparison of Affymetrix 10K2.0, 250K Nsp, and SNP6.0 arrays.
The Journal of molecular diagnostics : JMD - 1 Mar 2010
Hagenkord Jill M, Monzon Federico A, Kash Shera F, Lilleberg Stan, Xie Qingmei, Kant Jeffrey A
Abstract excerpt
Specific chromosomal alterations are recognized as important prognostic factors in chronic lymphocytic leukemia (CLL). Array-based karyotyping is gaining acceptance as an alternative to the standard fluorescence in situ hybridization (FISH) panel for detecting these aberrations. This study explores the optimum single nucleotide polymorphism (SNP) array probe density for routine clinical use, presents clinical...
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