Article
Genome-wide arrays in routine diagnostics of hematological malignancies.
Human mutation - 1 Jun 2012
Simons Annet, Sikkema-Raddatz Birgit, de Leeuw Nicole, Konrad Nicole Claudia, Hastings Rosalind J, Schoumans Jacqueline
Abstract excerpt
Over the last three decades, cytogenetic analysis of malignancies has become an integral part of disease evaluation and prediction of prognosis or responsiveness to therapy. In most diagnostic laboratories, conventional karyotyping, in conjunction with targeted fluorescence in situ hybridization analysis, is routinely performed to detect recurrent aberrations with prognostic implications. However, the genetic...
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