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Genomic arrays identify high-risk chronic lymphocytic leukemia with genomic complexity: a multi-center study

23 Jan 2020

Abstract excerpt

Complex karyotype (CK) identified by chromosome-banding analysis (CBA) has shown prognostic value in chronic lymphocytic leukemia (CLL). Genomic arrays offer high-resolution genome-wide detection of copy-number alterations (CNAs) and could therefore be well equipped to detect the presence of a CK. Current knowledge on genomic arrays in CLL is based on outcomes of single center studies, in which different cutoffs...

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PMID: 31974198
DOI: 10.3324/haematol.2019.239947

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