Article
Molecular allelokaryotyping of early-stage, untreated chronic lymphocytic leukemia.
Cancer - 15 Mar 2008
Lehmann Sören, Ogawa Seishi, Raynaud Sophie D, Sanada Masashi, Nannya Yasuhito, Ticchioni Michel, Bastard Christian, Kawamata Norihiko, Koeffler H Phillip
Abstract excerpt
BACKGROUND: To the authors' knowledge, genetic abnormalities in early-stage chronic lymphocytic leukemia (CLL) have not been examined fully. Single nucleotide polymorphism (SNP) genomic array (SNP-chip) is a new tool that can detect copy number changes and uniparental disomy (UPD) over the entire genome with very high resolution. METHODS: The authors performed SNP-chip analysis on 56 samples from patients with...
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