Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional MRI assessment of task-induced deactivation of the default mode network in Alzheimer's disease and at-risk older individuals.

Behavioural neurology - 1 Jan 2009

Pihlajamäki Maija, Sperling Reisa A

Abstract excerpt

Alzheimer's disease (AD) is the most common form of dementia in old age, and is characterized by prominent impairment of episodic memory. Recent functional imaging studies in AD have demonstrated alterations in a distributed network of brain regions supporting memory function, including regions of the default mode network. Previous positron emission tomography studies of older individuals at risk for AD have...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Mapping
Share to Cognition Disorders
Share to Image Processing, Computer-Assisted

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Memory

Share to Nerve Net

Share to Neuropsychological Tests

Share to Patient Selection

Share to Signal Processing, Computer-Assisted

Source

Open in PubMed Open full text

Identifiers

PMID: 19847047
DOI: 10.3233/BEN-2009-0231
PMCID: PMC5450588

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional MRI assessment of task-induced deactivation of the default mode network in Alzheimer's disease and at-risk older individuals.PMID 19847047Read ↗

Functional alterations in memory networks in early Alzheimer's disease.Semantic proximity Read ↗

Default mode network activity and white matter integrity in healthy middle-aged ApoE4 carriers.Semantic proximity Read ↗

Diagnostic power of default mode network resting state fMRI in the detection of Alzheimer's diseaseSemantic proximity Read ↗

Phenotypic regional functional imaging patterns during memory encoding in mild cognitive impairment and Alzheimer's disease.Semantic proximity Read ↗

Evidence of altered posteromedial cortical FMRI activity in subjects at risk for Alzheimer disease.Semantic proximity Read ↗

Identification of Alzheimer disease risk by functional magnetic resonance imaging.Semantic proximity Read ↗

Semantic memory activation in amnestic mild cognitive impairment.Semantic proximity Read ↗

Loss of functional connectivity is greater outside the default mode network in nonfamilial early-onset Alzheimer's disease variants.Semantic proximity Read ↗

Race modifies default mode network connectivity in Alzheimer’s diseaseSemantic proximity Read ↗

Use of functional magnetic resonance imaging in the early identification of Alzheimer's disease.Semantic proximity Read ↗

Genetic risk for Alzheimer's disease alters the five-year trajectory of semantic memory activation in cognitively intact elders.Semantic proximity Read ↗

Discriminant analysis of brain imaging data identifies subjects with early Alzheimer's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.