Tumor suppressive functions of p53.

Abstract excerpt

The majority of human cancers acquire mutations that abrogate the p53 tumor suppressor network and, as a consequence, p53 is one of the most extensively studied proteins in cancer research. Because of its potent tumor suppressive activity, it is widely assumed that a molecular understanding of p53 action will produce fundamental insights into natural processes that limit tumorigenesis and may identify key...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Apoptosis
• Share to Autophagy
• Share to Cell Cycle