Article
Regulation and function of the p53 tumor suppressor protein.
Current opinion in cell biology - 1 Jun 2001
Ryan K M, Phillips A C, Vousden K H
Abstract excerpt
Loss of the p53 tumor suppressor pathway contributes to the development of most human cancers. p53 is a nuclear protein that functions as a regulator of transcription. Significant advances have been made recently in our understanding of how p53 function is regulated and the mechanisms by which p53 mediates its effects.
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.