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Article

The MLH1 -93 promoter variant influences gene expression.

Cancer epidemiology - 1 Feb 2010

Mei Manxue, Liu Dong, Dong Shuo, Ingvarsson Sigurdur, Goodfellow Paul J, Chen Huiping

Abstract excerpt

The -93 SNP of MLH1 gene is associated with MLH1 gene methylation in endometrial and colorectal cancers. We undertook luciferase reporter assay and electrophoretic mobility shift assay (EMSA) to test whether the -93 SNP affects the MLH1 gene expression. The luciferase activity for -93A plasmid is...

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Source

Identifiers

PMID: 20060799
DOI: 10.1016/j.canep.2009.12.009

Genes

MLH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20060799-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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