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Article

Polymorphisms of MLH1 and MSH2 genes and the risk of lung cancer among never smokers.

Lung cancer (Amsterdam, Netherlands) - 1 Jun 2011

Lo Yen-Li, Hsiao Chin-Fu, Jou Yuh-Shan, Chang Gee-Chen, Tsai Ying-Huang, Su Wu-Chou, Chen Kuan-Yu, Chen Yuh-Min, Huang Ming-Shyan, Hsieh Wan-Shan, Chen Chien-Jen, Hsiung Chao A

Abstract excerpt

Mismatch repair (MMR) plays an important role in repairing nucleotide mismatches during DNA replication. Defects in MMR genes are associated with some sporadic tumors. MLH1 and MSH2 are two of the MMR genes. We conducted a case-control study to investigate the associations between the risk of lung cancer and genetic polymorphisms in the MLH1 and MSH2 genes. The SNP genotypes were determined in 730 lung cancer...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21093954
DOI: 10.1016/j.lungcan.2010.10.009

Genes

MLH1
MSH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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