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Article

p27KIP1 expression in gastric cancer: differential pathways in the histological subtypes associated with Helicobacter pylori infection.

Scandinavian journal of gastroenterology - 1 Apr 2010

Alves Markênia Kélia Santos, Lima Valeska Portela, André Angela Rosa, Ferreira Márcia Valéria Pitombeira, Barros Marcos Aurélio Pessoa, Rabenhorst Silvia Helena Barem

Abstract excerpt

OBJECTIVE: Decreases in p27(KIP1) and C-MYC expression have been associated with Helicobacter pylori infection. Furthermore, C-MYC seems to be a transcriptional repressor of p27(KIP1). Therefore, in a series of gastric adenocarcinomas we studied the association of p27(KIP1) expression with H. pylori genotype (vacA, cagA, cagE and virB11) and the involvement of C-MYC in this process. MATERIAL AND METHODS:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20059402
DOI: 10.3109/00365520903521566

Genes

MYC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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