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Prognostic significance of p21 <sup>WAF1/CIP1</sup> , p27 <sup>Kip1</sup> , p53 and E-cadherin expression in gastric cancer

4 May 2007

Abstract excerpt

BACKGROUND: Gastric carcinoma is characterised by numerous genetic and epigenetic alterations that influence cell cycle progression, apoptosis and DNA repair. These alterations include down-regulation of the cyclin-dependent kinase (CDK) inhibitors p21(WAF1/CIP1) and p27(Kip1), and mutations of the tumour suppressor protein p53 and the cell adhesion molecule E-cadherin. Combined evaluation of the prognostic...

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PMID: 17483253
DOI: 10.1136/jcp.2006.038976

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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