Article
Differential expression of MYC in H. pylori-related intestinal and diffuse gastric tumors.
Virchows Archiv : an international journal of pathology - 1 Jun 2011
Silva-Fernandes Isabelle Joyce de Lima, Alves Markênia Kélia Santos, Lima Valeska Portela, de Lima Marcos Antônio Pereira, Barros Marcos Aurélio Pessoa, Ferreira Márcia Valéria Pitombeira, Rabenhorst Silvia Helena Barem
Abstract excerpt
Evidence suggests that the carcinogenic process guided by Helicobacter pylori is related to the expression of cell cycle and apoptosis proteins as BCL-2, BAX, and MYC. However, the literature is conflicting regarding the expression frequency in the histological subtypes and did not consider cagA gene presence. To investigate the expression of these proteins considering the histological subtypes of gastric cancer...
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