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Article

Ultradeep sequencing of a human ultraconserved region reveals somatic and constitutional genomic instability.

PLoS biology - 1 Jan 2010

De Grassi Anna, Segala Cinzia, Iannelli Fabio, Volorio Sara, Bertario Lucio, Radice Paolo, Bernard Loris, Ciccarelli Francesca D

Abstract excerpt

Early detection of cancer-associated genomic instability is crucial, particularly in tumour types in which this instability represents the essential underlying mechanism of tumourigenesis. Currently used methods require the presence of already established neoplastic cells because they only detect...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20052272
DOI: 10.1371/journal.pbio.1000275
PMCID: PMC2794366

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20052272-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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