Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human genome ultraconserved elements are ultraselected.

Science (New York, N.Y.) - 17 Aug 2007

Katzman Sol, Kern Andrew D, Bejerano Gill, Fewell Ginger, Fulton Lucinda, Wilson Richard K, Salama Sofie R, Haussler David

Abstract excerpt

Ultraconserved elements in the human genome are defined as stretches of at least 200 base pairs of DNA that match identically with corresponding regions in the mouse and rat genomes. Most ultraconserved elements are noncoding and have been evolutionarily conserved since mammal and bird ancestors diverged over 300 million years ago. The reason for this extreme conservation remains a mystery. It has been speculated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bayes Theorem
Share to Conserved Sequence
Share to Gene Frequency

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome, Human

Share to Likelihood Functions

Share to Polymorphism, Single Nucleotide

Share to Selection, Genetic

Source

Identifiers

PMID: 17702936
DOI: 10.1126/science.1142430

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human genome ultraconserved elements are ultraselected.PMID 17702936Read ↗

The strength of selection on ultraconserved elements in the human genome.Semantic proximity Read ↗

Ultraconserved elements in the human genome.Semantic proximity Read ↗

Genetic Variations of Ultraconserved Elements in the Human Genome.Semantic proximity Read ↗

Widespread ultraconservation divergence in primates.Semantic proximity Read ↗

The evolution of ultraconserved elements with different phylogenetic origins.Semantic proximity Read ↗

The Functional Map of Ultraconserved Regions in Humans, Mice and RatsSemantic proximity Read ↗

SNPs in ultraconserved elements and familial breast cancer risk.Semantic proximity Read ↗

Ultraconserved elements in the human genome: association and transmission analyses of highly constrained single-nucleotide polymorphisms.Semantic proximity Read ↗

Deletion of ultraconserved elements yields viable mice.Semantic proximity Read ↗

UCbase 2.0: ultraconserved sequences database (2014 update).Semantic proximity Read ↗

Ultraconserved elements occupy specific arenas of three-dimensional mammalian genome organizationSemantic proximity Read ↗

Sequence variation in ultraconserved and highly conserved elements does not cause X-linked mental retardation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.