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Article

Genetic variants in ultraconserved regions associate with prostate cancer recurrence and survival.

Scientific reports - 23 Feb 2016

Bao Bo-Ying, Lin Victor C, Yu Chia-Cheng, Yin Hsin-Ling, Chang Ta-Yuan, Lu Te-Ling, Lee Hong-Zin, Pao Jiunn-Bey, Huang Chao-Yuan, Huang Shu-Pin

Abstract excerpt

Ultraconserved regions (UCRs) are DNA segments of longer than 200 bp in length that are completely conserved between human, rat, and mouse genomes. Recent studies have shown that UCRs are frequently located at fragile sites involved in cancers, and their levels of transcription can be altered during human tumorigenesis. We systematically evaluated 14 common single-nucleotide polymorphisms (SNPs) within UCRs in...

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Identifiers

PMID: 26902966
DOI: 10.1038/srep22124
PMCID: PMC4763269

Genes

NPAS3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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