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Article

Evaluation of selective competitive binding of basic drugs to alpha1-acid glycoprotein variants.

Biological & pharmaceutical bulletin - 1 Jan 2010

Ishizaki Junko, Fukaishi Akiko, Fukuwa Chie, Yamazaki Satoko, Tabata Mayu, Ishida Takuya, Suga Yukio, Arai Kunizo, Yokogawa Koichi, Miyamoto Ken-ichi

Abstract excerpt

We examined the binding of various basic drugs to the F(1)S and A genetic variants of alpha(1)-acid glycoprotein (AGP), which were isolated from native human commercial AGP (total AGP) by chromatography on an immobilized copper(II) affinity adsorbent. The values of the dissociation constant (K(d)...

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Identifiers

PMID: 20045943
DOI: 10.1248/bpb.33.95

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20045943-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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