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Article

The drug binding site of human alpha1-acid glycoprotein: insight from induced circular dichroism and electronic absorption spectra.

Biochimica et biophysica acta - 1 May 2007

Zsila Ferenc, Iwao Yasunori

Abstract excerpt

Human alpha(1)-acid glycoprotein (AGP) is an important drug binding plasma protein which affects pharmacokinetical properties of various therapeutic agents. For the first time, interpretation of the induced circular dichroism (ICD) spectra of drug-AGP complexes is presented yielding valuable information on the protein binding environment. ICD spectra were obtained by novel ligands of which AGP induced optical...

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Identifiers

PMID: 17321687
DOI: 10.1016/j.bbagen.2007.01.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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