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Article

Selective binding of tamsulosin to genetic variants of human alpha1-acid glycoprotein.

Biological & pharmaceutical bulletin - 1 Aug 2007

Hanada Kazuhiko, Tochikura Naohiro, Ogata Hiroyasu

Abstract excerpt

We investigated the characteristics of binding of tamsulosin to alpha(1)-acid glycoprotein (AGP) genetic variants. The binding of tamsulosin to each of the human AGP variants was determined by ultrafiltration, and the binding characteristics for each variant were compared using binding parameters and inhibition of the binding by disopyramide and warfarin. The affinities of tamsulosin binding to a F1/S variant...

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Identifiers

PMID: 17666829
DOI: 10.1248/bpb.30.1593

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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