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Article

Low-density lipoprotein receptor-related protein 5 (LRP5) variation in fracture prone children.

Bone - 1 Apr 2010

Saarinen Anne, Mäyränpää Mervi K, Lehesjoki Anna-Elina, Mäkitie Outi

Abstract excerpt

OBJECTIVE: Recent studies have confirmed that the low-density lipoprotein receptor-related protein 5 gene (LRP5), plays a role in bone mass accrual and in susceptibility to osteoporotic fractures in adults. This study evaluated whether LRP5 variation is implicated in childhood fractures. PATIENTS...

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Source

Identifiers

PMID: 20045498
DOI: 10.1016/j.bone.2009.12.022

Genes

LRP5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20045498-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Low-density lipoprotein receptor-related protein 5 (LRP5) variation in fracture prone children.PMID 20045498Read ↗

A haplotype-based analysis of the LRP5 gene in relation to osteoporosis phenotypes in Spanish postmenopausal women.Semantic proximity Read ↗

The genetics of low-density lipoprotein receptor-related protein 5 in bone: a story of extremes.Semantic proximity Read ↗

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Common Genetic Variation of the <i>Low-Density Lipoprotein Receptor-Related Protein 5</i> and <i>6</i> Genes Determines Fracture Risk in Elderly White MenSemantic proximity Read ↗

The Polygenic and Monogenic Basis of Paediatric Fractures.Semantic proximity Read ↗

LRP5-related primary osteoporosis: phenotypic spectrum and treatment response to zoledronic acid.Semantic proximity Read ↗

Wnt receptors, bone mass, and fractures: gene-wide association analysis of LRP5 and LRP6 polymorphisms with replication.Semantic proximity Read ↗

Common polymorphism in the LRP5 gene may increase the risk of bone fracture and osteoporosis.Semantic proximity Read ↗

The A1330V polymorphism of the low-density lipoprotein receptor-related protein 5 gene (LRP5) associates with low peak bone mass in young healthy men.Semantic proximity Read ↗

LRP5 gene polymorphisms predict bone mass and incident fractures in elderly Australian women.Semantic proximity Read ↗

Contribution of the LRP5 gene to normal variation in peak BMD in women.Semantic proximity Read ↗

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