Article
The A1330V polymorphism of the low-density lipoprotein receptor-related protein 5 gene (LRP5) associates with low peak bone mass in young healthy men.
Bone - 1 Apr 2007
Saarinen Anne, Välimäki Ville-Valtteri, Välimäki Matti J, Löyttyniemi Eliisa, Auro Kirsi, Uusen Piia, Kuris Mairi, Lehesjoki Anna-Elina, Mäkitie Outi
Abstract excerpt
INTRODUCTION: Polymorphisms in the gene coding for low-density lipoprotein receptor-related protein 5 (LRP5) contribute to variation in bone mass in the general population. Whether this is due to influence on bone mass acquisition or on bone loss thereafter has not been established. METHODS: We studied the association of LRP5 polymorphisms with peak bone mass in young men. The study included 235 Finnish men, aged...
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