Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Understanding the Impact of the Sirtuin 1 (SIRT1) Gene on Age-related Macular Degeneration: A Comprehensive Study.

The Nigerian postgraduate medical journal - 1 Apr 2024

Velmurugan Saranya, Pauline Rashmi, Chandrashekar Gurudeva, Kulanthaivel Langeswaran, Subbaraj Gowtham Kumar

Abstract excerpt

Age-related macular degeneration (AMD) is a prevalent and incurable condition affecting the central retina and posing a significant risk to vision, particularly in individuals over the age of 60. As the global population ages, the prevalence of AMD is expected to rise, leading to substantial socioeconomic impacts and increased healthcare costs. The disease manifests primarily in two forms, neovascular and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Predisposition to Disease
Share to Macular Degeneration

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Genetic

Share to Sirtuin 1

Source

Identifiers

PMID: 38826012
DOI: 10.4103/npmj.npmj_9_24

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Understanding the Impact of the Sirtuin 1 (SIRT1) Gene on Age-related Macular Degeneration: A Comprehensive Study.PMID 38826012Read ↗

Single Nucleotide Polymorphisms of the Sirtuin 1 (SIRT1) Gene are Associated With age-Related Macular Degeneration in Chinese Han Individuals: A Case-Control Pilot Study.Semantic proximity Read ↗

Role of Sirtuin 1 in the pathogenesis of ocular disease (Review)Semantic proximity Read ↗

Sirtuins Expression and Their Role in Retinal DiseasesSemantic proximity Read ↗

The role of sirtuin 1 in ageing and neurodegenerative disease: A molecular perspectiveSemantic proximity Read ↗

Protein Acetylation in Age-Related Macular Degeneration: Mechanisms, Roles, and Therapeutic PerspectivesSemantic proximity Read ↗

The many faces of SIRT6 in the retina and retinal pigment epitheliumSemantic proximity Read ↗

Age-Related Macular Degeneration: Cellular and Molecular Signaling MechanismsSemantic proximity Read ↗

Characterization of SIRT1/DNMTs Functions and LINE-1 Methylation in Patients with Age-Related Macular DegenerationSemantic proximity Read ↗

PGC-1α Protects RPE Cells of the Aging Retina against Oxidative Stress-Induced Degeneration through the Regulation of Senescence and Mitochondrial Quality Control. The Significance for AMD PathogenesisSemantic proximity Read ↗

Sirt1: A Guardian of the Development of Diabetic RetinopathySemantic proximity Read ↗

Age‐related macular degeneration—clinical review and genetics updateSemantic proximity Read ↗

Oxidative stress, innate immunity, and age-related macular degenerationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.