Article
Pitfalls in the use of voxel-based morphometry as a biomarker: examples from huntington disease.
AJNR. American journal of neuroradiology - 1 Apr 2010
Henley S M D, Ridgway G R, Scahill R I, Klöppel S, Tabrizi S J, Fox N C, Kassubek J
Abstract excerpt
BACKGROUND AND PURPOSE: VBM is increasingly used in the study of neurodegeneration, and recently there has been interest in its potential as a biomarker. However, although it is largely "automated," VBM is rarely implemented consistently across studies, and changing user-specified options can alter the results in a way similar to the very biologic differences under investigation. MATERIALS AND METHODS: This work...
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