Article

White matter changes in Huntington’s disease and the demyelination hypothesis: a critical review

2019-12-24

Abstract excerpt

<p>Huntington’s disease (HD) is a genetic neurodegenerative disorder, characterised by atrophy of the neostriatum, and cortical grey matter abnormalities. White matter (WM) alterations have recently been identified as a relevant pathophysiological feature of HD, but the etiology of WM degeneration, and its role in disease pathogenesis and progression remain unclear. An increasing body of research suggests that WM...

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Literature Corpus work: 03e6b138-bbfe-582c-8cae-1d3c7d7e2389
DOI: 10.31234/osf.io/u8p9b

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