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Voxel-based morphometry in tau-positive and tau-negative frontotemporal lobar degenerations.

Neuro-degenerative diseases - 1 Jan 2004

Whitwell Jennifer L, Warren Jason D, Josephs Keith A, Godbolt Alison K, Revesz Tamas, Fox Nick C, Rossor Martin N

Abstract excerpt

BACKGROUND: The identification of specific, diagnostically useful predictors of protein dysfunction in the frontotemporal lobar degenerations (FTLD) is a problem of great clinical and biological interest. Correlations between regional patterns of tissue loss and specific proteinopathies have not been established. OBJECTIVE: Specific brain imaging correlates of protein tau dysfunction were sought using voxel-based...

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Dementia
Image Processing, Computer-Assisted
Magnetic Resonance Imaging
Phenotype
tau Proteins

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PMID: 16908994
DOI: 10.1159/000080990

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