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Article

Voxel-based morphometry with templates and validation in a mouse model of Huntington's disease.

Magnetic resonance imaging - 1 Nov 2013

Sawiak Stephen J, Wood Nigel I, Williams Guy B, Morton A Jennifer, Carpenter T Adrian

Abstract excerpt

Despite widespread application to human imaging, voxel-based morphometry (VBM), where images are compared following grey matter (GM) segmentation, is seldom used in mice. Here VBM is performed for the R6/2 model of Huntington's disease, a progressive neurological disorder. This article discusses issues in translating the methods to mice and shows that its statistical basis is sound in mice as it is in human...

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Identifiers

PMID: 23835187
DOI: 10.1016/j.mri.2013.06.001
PMCID: PMC3919157

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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