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Article

Angiotensin II AT2 receptor regulates ureteric bud morphogenesis.

American journal of physiology. Renal physiology - 1 Mar 2010

Song Renfang, Spera Melissa, Garrett Colleen, El-Dahr Samir S, Yosypiv Ihor V

Abstract excerpt

ANG II AT2 receptor (AT2R)-deficient mice exhibit abnormal ureteric bud (UB) budding, increased incidence of double ureters, and vesicoureteral reflux. However, the role of the AT2R during UB morphogenesis and the mechanisms by which aberrant AT2R signaling disrupts renal collecting system development have not been fully defined. In this study, we mapped the expression of the AT2R during mouse metanephric...

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Source

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Identifiers

PMID: 20032120
DOI: 10.1152/ajprenal.00147.2009
PMCID: PMC2838588

Genes

GDNF
ANG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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