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Article

Molecular mechanism of ureteric bud development.

Seminars in cell & developmental biology - 1 Aug 2003

Sakurai Hiroyuki

Abstract excerpt

The urinary collecting system is derived from an epithelial protrusion arising from the Wolffian duct called the ureteric bud (UB) by the signal from its inductive tissue, metanephric mesenchyme (MM). Targeted gene mutation studies have shown that several transcription factors and MM-secreted glial cell line-derived neurotrophic factor (GDNF) are critical for initiation of the UB. After initiation, the UB...

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Source

Identifiers

PMID: 14627120
DOI: 10.1016/s1084-9521(03)00024-7

Genes

GDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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