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Article

Heterogeneity in the clonal T cell response. Implications for models of T cell activation and cytokine phenotype development.

Immunologic research - 1 Jan 1998

Weaver C T, Saparov A, Kraus L A, Rogers W O, Hockett R D, Bucy R P

Abstract excerpt

The T cell can be defined in the context of two properties--the recognition specificity of the T cell receptor (TCR) heterodimer and the functional response of the T cell after TCR stimulation. Once a particular TCR heterodimer is expressed and successfully selected during thymic development, the antigen specificity is fixed for all the clonal progeny of that cell. In contrast, the potential functional responses...

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PMID: 9638473
DOI: 10.1007/BF02786452

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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