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Article

CD28 mRNA rapidly decays when activated T cells are functionally anergized with specific peptide.

International immunology - 1 May 1993

Lake R A, O'Hehir R E, Verhoef A, Lamb J R

Abstract excerpt

The induction of non-responsiveness in specific clones of T cells in vivo might be expected to reverse immunologically mediated disease processes. With this goal in mind, experiments in vitro with cloned T cells have investigated the mechanisms of induction of anergy. Resting T cells can be functionally inactivated in vitro by high doses of appropriate peptide in either the presence or absence of antigen...

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Identifiers

PMID: 8391307
DOI: 10.1093/intimm/5.5.461

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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