Article
Selection of genetic variants of simian immunodeficiency virus in persistently infected rhesus monkeys.
Journal of virology - 1 Apr 1991
Burns D P, Desrosiers R C
Abstract excerpt
Genetic and antigenic variation may be one means by which lentiviruses that cause AIDS avoid elimination by host immune responses. Genetic variation in the envelope gene (env) was studied by comparing the nucleotide sequences of 27 clones obtained from two rhesus monkeys infected with molecularly cloned simian immunodeficiency virus. All 27 clones differed from each other and differed from the input clone in the...
Topics
- Amino Acid Sequence
- Animals
- Antibodies, Viral
- Antigenic Variation
- Base Sequence
- Cell Line
- Cloning, Molecular
- Gene Products, env
- Genotype
- Immunoglobulin Variable Region
- Macaca mulatta