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Article

Simian immunodeficiency virus mutants resistant to serum neutralization arise during persistent infection of rhesus monkeys.

Journal of virology - 1 Jul 1993

Burns D P, Collignon C, Desrosiers R C

Abstract excerpt

We previously described the pattern of sequence variation in gp120 following persistent infection of rhesus monkeys with the pathogenic simian immunodeficiency virus SIVmac239 molecular clone (D.P.W. Burns and R.C. Desrosiers, J. Virol. 65:1843, 1991). Sequence changes were confined largely to five variable regions (V1 to V5), four of which correspond to human immunodeficiency virus type 1 (HIV-1) gp120 variable...

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Identifiers

PMID: 8510218
DOI: 10.1128/JVI.67.7.4104-4113.1993
PMCID: PMC237779

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