Article
Simian immunodeficiency virus mutants resistant to serum neutralization arise during persistent infection of rhesus monkeys.
Journal of virology - 1 Jul 1993
Burns D P, Collignon C, Desrosiers R C
Abstract excerpt
We previously described the pattern of sequence variation in gp120 following persistent infection of rhesus monkeys with the pathogenic simian immunodeficiency virus SIVmac239 molecular clone (D.P.W. Burns and R.C. Desrosiers, J. Virol. 65:1843, 1991). Sequence changes were confined largely to fi...
Topics
- Amino Acid Sequence
- Animals
- Antibodies, Viral
- Antigens, Viral
- Cloning, Molecular
- DNA, Recombinant
- HIV Envelope Protein gp120
- Macaca mulatta
- Membrane Glycoproteins
- Molecular Sequence Data
- Mutation
- Neutralization Tests
- Sequence Alignment
- Simian Acquired Immunodeficiency Syndrome
- Simian Immunodeficiency Virus
- Structure-Activity Relationship
- Time Factors
- Transfection