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Article

Induction of AIDS in Rhesus Monkeys by Molecularly Cloned Simian Immunodeficiency Virus

1 Jun 1990

Abstract excerpt

Better understanding of the pathogenesis of acquired immunodeficiency syndrome (AIDS) would be greatly facilitated by a relevant animal model that uses molecularly cloned virus of defined sequence to induce the disease. Such a system would also be of great value for AIDS vaccine research. An infectious molecular clone of simian immunodeficiency virus (SIV) was identified that induces AIDS in common rhesus monkeys...

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Identifiers

PMID: 2160735
DOI: 10.1126/science.2160735

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Source receipt: pubmed, retrieved 7 Sept 2026.

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