Article
Development of vivo of genetic variability of simian immunodeficiency virus.
Proceedings of the National Academy of Sciences of the United States of America - 15 Sept 1991
Baier M, Dittmar M T, Cichutek K, Kurth R
Abstract excerpt
Rapid development of genetic variability may contribute to the pathogenicity of lentiviruses as it may allow escape from immune surveillance and/or from suppression of virus replication. Although apathogenic in African green monkeys, simian immunodeficiency virus isolated from African green monkeys is shown to display extensive genetic variability and defectiveness in the V1- and V2-like variable domains of the...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Chlorocebus aethiops
- Cloning, Molecular
- Genes, env
- Molecular Sequence Data
- Mutation
- Oligonucleotides
- Polymerase Chain Reaction
- Simian Acquired Immunodeficiency Syndrome