Article
The genetic evolution of the envelope gene of simian immunodeficiency virus in cynomolgus macaques infected with a complex virus pool.
Virology - 1 Dec 1992
Almond N, Jenkins A, Heath A B, Taffs L F, Kitchin P
Abstract excerpt
Two cynomolgus macaques were infected with a complex, but characterized, challenge stock of simian immunodeficiency virus (SIVmac251 32H). The polymerase chain reaction was applied in a temporal sequence analysis to determine the sequences of the gp120 region of the SIV env gene, which were present in the blood of both macaques at 1, 6, and 15 months postinfection (p.i.). At 1 month p.i. selected sequences, which...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Biological Evolution
- Disease Models, Animal
- Genes, env
- Genetic Variation
- HIV Envelope Protein gp120
- Macaca fascicularis
- Membrane Glycoproteins
- Molecular Sequence Data