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Article

Why some photoreceptors die, while others remain dormant: lessons from RPE65 and LRAT associated retinal dystrophies.

Ophthalmic genetics - 1 Jun 2011

Koenekoop Robert K

Abstract excerpt

PURPOSE: Why some photoreceptors die and other do not is not well understood, but is a fascinating and important emerging concept, now that gene and drug therapy have shown preliminary positive results in treatments for patients with gene specific retinal degenerations. RESULTS: This review discusses these concepts and a new study that shows that continuous activation of the phototransduction cascade activates...

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Source

Identifiers

PMID: 21268677
DOI: 10.3109/13816810.2010.544361

Genes

LRAT
RPE65

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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