Article
Association between the IL-4 promoter polymorphisms and asthma or severity of hyperresponsiveness in Taiwanese.
Respirology (Carlton, Vic.) - 1 Jan 2007
Chiang Chi-Huei, Tang Ying-Chuan, Lin Ming-Wei, Chung Ming-Yi
Abstract excerpt
BACKGROUND AND OBJECTIVES: Recent family-based studies have revealed a linkage between human chromosome 5q31 and asthma, elevated serum IgE levels and airway hyperresponsiveness (AHR). Among the candidate genes in this region is the gene encoding IL-4. This gene could be a candidate gene for asthma. The aim of this prospective case-control study was to assess the frequency of polymorphisms in the IL-4 gene...
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