Functional polymorphism in CTLA4 gene influences the response to therapy with inhaled corticosteroids in Slovenian children with atopic asthma.

doi:10.3109/13547500903384318

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Functional polymorphism in CTLA4 gene influences the response to therapy with inhaled corticosteroids in Slovenian children with atopic asthma.

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 Mar 2010

Berce Vojko, Potocnik Uros

Abstract excerpt

We genotyped CTLA4 CT60 (rs3087243) functional single nucleotide polymorphism (SNP) in children with asthma and in healthy controls and correlated the genotype data with asthma clinical data, including treatment response with inhaled corticosteroids measured by forced expiratory volume in the first second (FEV(1)). FEV(1) increased by 21.7% after 4 weeks of therapy in atopic asthmatics with the A/A genotype...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adrenal Cortex Hormones

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Anti-Asthmatic Agents

Share to Antigens, CD

Share to Asthma

Share to CD28 Antigens

Share to CTLA-4 Antigen

Share to Forced Expiratory Volume

Share to Slovenia

Source

Open in PubMed

Identifiers

PMID: 19895365
DOI: 10.3109/13547500903384318

Genes

CTLA4
FEV

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional polymorphism in CTLA4 gene influences the response to therapy with inhaled corticosteroids in Slovenian children with atopic asthma.PMID 19895365Read ↗

CTLA4 CT60 single-nucleotide polymorphism is associated with Slovenian inflammatory bowel disease patients and regulates expression of CTLA4 isoforms.Semantic proximity Read ↗

Association of plasma soluble CTLA-4 with lung function and gene polymorphism in Chinese asthmatic children.Semantic proximity Read ↗

A meta-analysis of the association between CTLA-4 genetic polymorphism and susceptibility of asthma.Semantic proximity Read ↗

IL-4-C-590T locus polymorphism and susceptibility to asthma in children: a meta-analysis.Semantic proximity Read ↗

Cytotoxic T-lymphocyte associated antigen 4 polymorphisms and asthma risk: a meta-analysis.Semantic proximity Read ↗

CT60 genotype does not affect CTLA-4 isoform expression despite association to T1D and AITD in northern Sweden.Semantic proximity Read ↗

Interleukin-4 rs2243250 polymorphism is associated with asthma among Caucasians and related to atopic asthma.Semantic proximity Read ↗

CTLA-4 polymorphisms in allergy and asthma and the TH1/ TH2 paradigm.Semantic proximity Read ↗

Polymorphisms within the CTLA4 gene are associated with infant atopic dermatitis.Semantic proximity Read ↗

Association between Interleukin-4-590C>T Polymorphism and the Susceptibility to Asthma: A Meta-Analysis of Case-Control Study.Semantic proximity Read ↗

Genetic association study of CTLA4 and FCεRIα polymorphisms in asthmatic patients in the southwestern region of Iran.Semantic proximity Read ↗

Allelic variant in CTLA4 alters T cell phosphorylation patterns.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.