Interleukin 4 gene polymorphism (-589C/T) and the risk of asthma: a meta-analysis and met-regression based on 55 studies.

doi:10.1186/s12865-020-00384-7

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Article

Interleukin 4 gene polymorphism (-589C/T) and the risk of asthma: a meta-analysis and met-regression based on 55 studies.

BMC immunology - 21 Oct 2020

Kousha Ahmad, Mahdavi Gorabi Armita, Forouzesh Mehdi, Hosseini Mojgan, Alexander Markov, Imani Danyal, Razi Bahman, Mousavi Mohammad Javad, Aslani Saeed, Mikaeili Haleh

Abstract excerpt

BACKGROUND: Numerous investigations have previously evaluated the association of interleukin (IL) 4 gene polymorphisms and the risk of asthma, conferring inconsistent results. To resolve the incongruent outcomes yielded from different single studies, we conducted the most up-to-date meta-analysis...

Topics

Alleles
Asthma
Case-Control Studies
Ethnicity
Genetic Association Studies
Genetic Predisposition to Disease
Genotype
Humans
Interleukin-4
Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 33087044
DOI: 10.1186/s12865-020-00384-7
PMCID: PMC7579954

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-33087044-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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