Article
Genetic association study of CTLA4 and FCεRIα polymorphisms in asthmatic patients in the southwestern region of Iran.
Nucleosides, nucleotides & nucleic acids - 1 Jan 2021
Roshanizadeh Zahra, Ghandil Pegah, Khodadadi Ali, Tavakol Heshmatollah, Kambiz Ahmadi Angali, Ghadiri Ata
Abstract excerpt
Asthma is a heterogeneous chronic pulmonary disease that develops due to the interaction of genetic and environmental factors. This study aimed to investigate the polymorphisms of CTLA4(SNP-318C > T, SNP + 49A > G) and FCεRIα(SNP-344T > C) genes in asthmatic patients in Southwest Iran. The study enrolled 200 patients with asthma of Arab and Bakhtiary descent and 200 healthy controls, where asthmatic patients and...
Topics
- Adolescent
- Adult
- Age Factors
- Aged
- Asthma
- CTLA-4 Antigen
- Child
- Child, Preschool
- Female
- Genetic Association Studies
- Genetic Predisposition to Disease
