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Article

CTLA-4 polymorphisms in allergy and asthma and the TH1/ TH2 paradigm.

The Journal of allergy and clinical immunology - 1 Aug 2004

Munthe-Kaas Monica Cheng, Carlsen Kai Håkon, Helms Peter J, Gerritsen Jorrit, Whyte Moira, Feijen Marlies, Skinningsrud Beate, Main Margaret, Kwong Georges Ng Man, Lie Benedicte A, Lødrup Carlsen Karin C, Undlien Dag E

Abstract excerpt

BACKGROUND: Several genomic regions are reported to be associated with the development of asthma and allergy, including chromosome 2q33. This region harbors the candidate gene cytotoxic T-lymphocyte antigen 4 (CTLA-4), an important regulator of T-cell activation and differentiation. OBJECTIVE: We...

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Source

Identifiers

PMID: 15316504
DOI: 10.1016/j.jaci.2004.03.050

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15316504-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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