Article
Mutation screening and assessment of the effect of genetic variations on expression and RNA editing of serotonin receptor 2C in the human brain.
Psychiatry and clinical neurosciences - 1 Feb 2010
Bundo Miki, Iwamoto Kazuya, Yamada Kazuo, Yoshikawa Takeo, Kato Tadafumi
Abstract excerpt
AIM: Serotonin receptor 2C (HTR2C) has been postulated as being involved in the etiology or pathophysiology of mental disorders such as bipolar disorder, major depression and schizophrenia. We previously revealed the altered mRNA expression and RNA editing of HTR2C in the postmortem brains of patients with mental disorders. Here we examined the relationship between genetic variations and expression level or RNA...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
