Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Serotonin receptor 2C (HTR2C) and schizophrenia: examination of possible medication and genetic influences on expression levels.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Apr 2005

Castensson Anja, Aberg Karolina, McCarthy Shane, Saetre Peter, Andersson Björn, Jazin Elena

Abstract excerpt

The serotonin receptor 2C (HTR2C) gene is of interest in schizophrenia due to its involvement in regulation of dopamine activity in the prefrontal cortex. We have previously reported a decreased expression of HTR2C mRNA levels in the prefrontal cortex of schizophrenia patients. The variability in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antipsychotic Agents
Share to Frontal Lobe

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation

Share to Haplotypes

Share to Promoter Regions, Genetic

Share to Receptor, Serotonin, 5-HT2C

Share to RNA, Messenger

Share to Schizophrenia

Source

Identifiers

PMID: 15717293
DOI: 10.1002/ajmg.b.30151

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15717293-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Serotonin receptor 2C (HTR2C) and schizophrenia: examination of possible medication and genetic influences on expression levels.PMID 15717293Read ↗

Mutation screening and assessment of the effect of genetic variations on expression and RNA editing of serotonin receptor 2C in the human brain.Semantic proximity Read ↗

Serotonin receptor 2C and mental disorders: genetic, expression and RNA editing studies.Semantic proximity Read ↗

Epigenetic dysregulation of HTR2A in the brain of patients with schizophrenia and bipolar disorder.Semantic proximity Read ↗

Serotonin subtype 2 receptor genes and clinical response to clozapine in schizophrenia patients.Semantic proximity Read ↗

Schizophrenia and the serotonin-2A receptor promoter polymorphism.Semantic proximity Read ↗

5-HT2C receptor gene polymorphisms associated with antipsychotic drug action alter promoter activitySemantic proximity Read ↗

Monoallelic and unequal allelic expression of the HTR2A gene in human brain and peripheral lymphocytes.Semantic proximity Read ↗

HTR2A gene variants and psychiatric disorders: a review of current literature and selection of SNPs for future studies.Semantic proximity Read ↗

HTR2A: Association and expression studies in neuropsychiatric geneticsSemantic proximity Read ↗

The serotonin-2A receptor gene locus does not contain common polymorphism affecting mRNA levels in adult brain.Semantic proximity Read ↗

Supportive evidence for the association between the T102C 5-HTR2A gene polymorphism and schizophrenia: a large-scale case-control and family-based study.Semantic proximity Read ↗

RNA editing of the 5-HT(2C) receptor is reduced in schizophrenia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.