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Article

Genomic structure and expression of the human serotonin 2A receptor gene (HTR2A) locus: identification of novel HTR2A and antisense (HTR2A-AS1) exons.

BMC genetics - 6 Jan 2016

Ruble Cara L, Smith Ryan M, Calley John, Munsie Leanne, Airey David C, Gao Yuan, Shin Joo Heon, Hyde Thomas M, Straub Richard E, Weinberger Daniel R, Nisenbaum Laura K

Abstract excerpt

BACKGROUND: The serotonin 2A receptor is widely implicated in genetic association studies and remains an important drug target for psychiatric, neurological, and cardiovascular conditions. RNA sequencing redefined the architecture of the serotonin 2A receptor gene (HTR2A), revealing novel mRNA transcript isoforms utilizing unannotated untranslated regions of the gene. Expression of these untranslated regions is...

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Identifiers

PMID: 26738766
DOI: 10.1186/s12863-015-0325-6
PMCID: PMC4702415

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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