Article
Bioinformatic analyses to select phenotype affecting polymorphisms in HTR2C gene.
Human psychopharmacology - 1 Aug 2011
Piva Francesco, Giulietti Matteo, Baldelli Luisa, Nardi Bernardo, Bellantuono Cesario, Armeni Tatiana, Saccucci Franca, Principato Giovanni
Abstract excerpt
OBJECTIVE: Single nucleotide polymorphisms (SNPs) in serotonin related genes influence mental disorders, responses to pharmacological and psychotherapeutic treatments. In planning association studies, researchers that want to investigate new SNPs have to select some among a large number of candidates. Our aim is to guide researchers in the selection of the most likely phenotype affecting polymorphisms. Here, we...
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