Article
Now and future of mouse mutagenesis for human disease models.
Journal of genetics and genomics = Yi chuan xue bao - 1 Sept 2010
Gondo Yoichi
Abstract excerpt
One of the major objectives of the Human Genome Project is to understand the biological function of the gene and genome as well as to develop clinical applications for human diseases. For this purpose, the experimental validations and preclinical trails by using animal models are indispensable. The mouse (Mus musculus) is one of the best animal models because genetics is well established in the mouse and...
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