Article
Reduced hippocampal CA2, CA3, and dentate gyrus activity in asymptomatic people at genetic risk for Alzheimer's disease.
NeuroImage - 15 Nov 2010
Suthana Nanthia A, Krupa Allison, Donix Markus, Burggren Alison, Ekstrom Arne D, Jones Michael, Ercoli Linda M, Miller Karen J, Siddarth Prabha, Small Gary W, Bookheimer Susan Y
Abstract excerpt
Previous functional magnetic resonance imaging (MRI) studies in healthy subjects with the apolipoprotein Eepsilon4 (APOE-4) genetic risk for Alzheimer's disease have shown increased activation during memory task performance in broadly distributed cortical regions. These findings have been hypothe...
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