Article
Aurora-A overexpression enhances cell-aggregation of Ha-ras transformants through the MEK/ERK signaling pathway.
BMC cancer - 12 Dec 2009
Tseng Ya-Shih, Lee Jenq-Chang, Huang Chi-Ying F, Liu Hsiao-Sheng
Abstract excerpt
BACKGROUND: Overexpression of Aurora-A and mutant Ras (RasV12) together has been detected in human bladder cancer tissue. However, it is not clear whether this phenomenon is a general event or not. Although crosstalk between Aurora-A and Ras signaling pathways has been reported, the role of these...
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