Article
Evidence for an association of HLA-DRB1*15 and DRB1*09 with leprosy and the impact of DRB1*09 on disease onset in a Chinese Han population.
BMC medical genetics - 11 Dec 2009
Zhang Furen, Liu Hong, Chen Shumin, Wang Changyuan, Zhu Chuanfu, Zhang Lin, Chu Tongsheng, Liu Dianchang, Yan Xiaoxiao, Liu Jianjun
Abstract excerpt
BACKGROUND: Human leukocyte antigens (HLAs) have been proposed to modulate the immune response to Mycobacterium leprae. The association of HLA-DRB1 with leprosy has been reported in several populations, but not in a Chinese population. METHODS: The polymerase chain reaction-sequence-specific olig...
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