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Article

Association of HLA-DRB alleles and pulmonary tuberculosis in North Chinese patients.

Genetics and molecular research : GMR - 5 Jul 2011

Shi G L, Hu X L, Yang L, Rong C L, Guo Y L, Song C X

Abstract excerpt

Human leukocyte antigen (HLA) plays a central role in the regulation of the immune response. HLA class II molecules are essential for T cell-mediated adaptive immunity and present peptide antigens to CD4(+) T cells. Because of its important role in the immune response and its high degree of polymorphism, the HLA system is associated with many diseases. We examined the polymorphisms of HLA-DRB alleles and the...

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Identifiers

PMID: 21751159
DOI: 10.4238/vol10-3gmr1132

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